If we can't see it, can't smell it, can't hear it and can't touch it, does it exist? If you're talking about an environmental hormone disrupter called BPA (bisphenol A), the answer is yes!
None of us can any longer hide our heads in the sand and pretend that environmental chemicals are having no effect on PCOS and our collective health.
The evidence is in. The chemical Genie is out of the bottle. We have a serious problem to solve.
Researchers in the UK and Greece have just published a report. The report says that women with polycystic ovary syndrome have a significantly higher body burden of bisphenol A (BPA) than other women.
BPA, a chemical in our environment, is a known estrogenic "hormone disrupter".
The study compared 71 women with PCOS to 100 "normal" women. All women were subdivided into lean and overweight groups.
All together, the polycystic ovarian syndrome women had 1.5 times the amount of BPA in their blood than the other women did.
The lean PCOS women had 1.6 times the amount compared to other lean women. The overweight women with the disorder had 1.3 times as much as the other overweight women.
The overweight women tended to have lower BPA levels in their blood than the lean ones. We can speculate that in the overweight women, they have more BPA stored in their fat cells and not as much in their blood. Fat cells are excellent storage sites for many environmental chemicals.
The study also established a close correlation between BPA levels and the level of male hormones such as testosterone. A close association was also shown between BPA and insulin resistance. In other words, the higher the BPA, the higher the male hormones and insulin resistance are.
Please note that high levels of male hormones and insulin resistance are believed to be the reason why you have this polycystic disease.
The study concluded: "Higher BPA levels in PCOS women compared to controls and a statistically significant positive association between androgens and BPA point to a potential role of this endocrine disruptor in PCOS pathophysiology."
They are implying that BPA appears to be a partial cause of this disease.
But there's more.
Shanghai Jiao Tong University in China just came out with this disturbing report. Their researchers collected the follicular fluid and ovarian cells from patients with polycystic ovary syndrome and patients without the disease.
They found that the level of BPA in the follicular fluid of the polycystic ovarian diseased women was roughly 23% higher than in the other women. Also, they added varying amounts of BPA to the collected ovarian cells. They said that synthesis of one of the estrogens was suppressed -- but only in the PCOS cells, not the cells from the other women. Ditto for an enzyme (aromatase), which converts male hormones into estrogen.
In other words, emerging evidence is showing that the increased levels of BPA found in women with polycystic ovary syndrome is leading to hormonal disruptions and actually making polycystic ovarian syndrome worse that it has to be.
What happens if you conceive? What happens to your developing baby?
In lab animals, BPA passes from the mother to the fetus. So BPA is still available to do its damage. Fetuses have a severely limited capability to detoxify chemicals such as BPA. Essentially, your future baby is at increased risk for problems that go far beyond PCOS or infertility.
For example, the University of North Carolina-Chapel Hill has reported that the 2-year old children of mothers with higher levels of BPA had more disturbed behavior. This was more pronounced in female children than males.
What happens if your new baby is exposed to BPA? If rodent studies are any clue, both your male and female babies will tend to be less fertile when they become adults.
For example, the University of Buenos Aires in Argentina recently completed a study of baby female rats exposed to BPA.
When the female rats became adults, they discovered that their BPA exposure was associated with increased testosterone and estrogen, and reduced progesterone. (This is an unbalanced hormone pattern commonly seen in women who have PCOS).
In addition, the exposed female rats had much reduced fertility. Also, their ovaries had large numbers of ovarian cysts.
If it can happen to a rat, can it happen to you? Think of the rats as canaries in a coal mine. If the canary dies, the miners are in trouble. One recent study showed that 99% of pregnant women had at least one urine sample with detectable levels of BPA. That's 99 of every 100 women!
The University Federico II in Italy published a study of 20 overweight women with polycystic ovary syndrome, who were compared to 20 normal overweight women.
As expected, the PCOS women had higher levels of BPA. They also had a higher level of insulin resistance, fatty liver degeneration, male hormones, inflammation -- and they had larger spleens.
An enlarged spleen is a sign of trouble.
Your spleen is an organ in the upper left of your abdomen. It is part of your blood management system and immune system. An enlarged spleen can be caused by many things, including mononucleosis, some cancers, or liver disease. In the case of polycystic ovarian syndrome, we might speculate that liver problems are burdening the spleen. I really don't know.
In any case, if you have a BPA burden, your entire body is being adversely affected. BPA is an invisible ball and chain that holds back your every effort to escape your situation and get healthier.
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Dec 04, 16 07:26 PM
Thank you for your newsletter! I have found it difficult to find useful, outside-the-box information on PCOS. I'm not a huge researcher because I find
Dec 04, 16 02:58 PM
Women with PCOS-related hirsutism, hair loss and acne may be treated with spironolactone (Aldactone), cyproterone acetate, flutamide (Eulexin), or finasteride (Propecia, Proscar).
Nov 27, 16 03:43 PM
I was diagnosed with PCOS at the age of 19. I am now 39 and finally have health coverage after 10 years. Doctors all throughout the past 20 years have