Supplemental inositol has a multitude of possible uses in relation to PCOS.
On this page, we talk about how inositol reduces the severity of acne and unwanted hair growth, lowers your testosterone levels, and reduces insulin resistance.
Vita-Salute University in Italy recently studied fifty women who had polycystic ovary syndrome. They took supplemental inositol for six months to determine its effects on skin conditions such as hirsutism (excess hair) and acne.
After 3 months of taking inositol, the women had reduced testosterone and improved insulin function.
In addition, after 6 months on the inositol, they also had significant reductions of both hirsutism and acne.
The researchers concluded: Inositol "is a simple and safe treatment that
ameliorates the metabolic profile of patients with PCOS, reducing
hirsutism and acne."
As the researchers say, inositol supplementation is both simple and safe. If taken over the span of half a year, it appears to reduce acne and hirsutism problems.
There's good news from Azienda USL hospital in Italy. In this study, 42 women with PCOS were treated. One group took folic acid (a B vitamin). The other group took folic acid plus inositol.
The women taking inositol had a dramatic drop in their testosterone levels; their testosterone levels were only about 1/3 of what they were before taking the inositol. (Women with polycystic ovary syndrome typically have excessive levels of the male hormone testosterone, which leads to problems such as a lack of ovulation, hirsutism, hair loss and acne.)
In addition, the women taking inositol reduced their triglycerides and blood pressure. Their insulin sensitivity also significantly improved.
The women who took only the folic acid experienced minor improvements which paled in comparison to those taking both folic acid and inositol.
The women taking inositol also achieved better ovulation: 16 of 23 women in inositol group ovulated vs. only 4 of 19 in other group.
It helps you reduce symptoms of polycystic ovarian syndrome related to insulin resistance.
Inositol is a component of a "second messenger system" inside the cell that allows insulin to change the behavior of the cell. But in some women who have PCOS, there appears to be a breakdown in the relationship between insulin and this second messenger system.
The result of this breakdown is insulin resistance. With the insulin resistance comes all of the problems you know so well: infertility, hirsutism, acne, hair loss, weight problems, cardiovascular disease and diabetes.
Inositol and its biochemical cousins, d-Pinitol and D-chiro-inositol, improve the insulin message system in your body so that insulin can do a more effective job of controlling your blood sugar. In other words, inositol can reduce a condition called "insulin resistance", which is thought to be a root cause of polycystic ovary syndrome.
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Thank you for your newsletter! I have found it difficult to find useful, outside-the-box information on PCOS. I'm not a huge researcher because I find
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Women with PCOS-related hirsutism, hair loss and acne may be treated with spironolactone (Aldactone), cyproterone acetate, flutamide (Eulexin), or finasteride (Propecia, Proscar).